Relationship between svo2 and scvo2 in shock

Venous Oximetry Overview

relationship between svo2 and scvo2 in shock

Thus, ScvO2 is not S¯vO2 (41), and the relationship between these two variables changes with . (Figure 4). In rare patients with extreme vasodilatory shock or . Shunt fraction = (1 2 SaO2)/(1 2 SvO2). For example, when. Central venous (ScvO2) and mixed venous oxygen saturation (SvO2) are measurements of the relationship between oxygen consumption and oxygen delivery. SvO2 (mixed venous oxygen saturation) or ScvO2 central venous A true mixed venous sample (called SvO2) is drawn from the tip of the It can be seen in late septic shock, or in cell poisoning such as . Community Links.

It is basically the percentage of oxygen remaining in the venous blood returning to the right side of the heart. This is the oxygen left over in the blood after supplying all the parts of the body except the head. Scvo2 stands for central venous oxygen saturation.


It is the oxygen saturation of venous blood coming from the head and upper body. It is measured from the superior vena cava, that drains blood from the head and upper body to the heart and thus, it is called as central venous oxygen saturation. This is because the lower half of the body extracts less oxygen and the brain extracts more oxygen than other organs of the body. Together, both the saturation percentages give us knowledge about the balance between the delivery of oxygen and oxygen consumption in the body.

The procedure for assessing Scvo2 is less risky and has far lesser complications than measuring Svo2. While collecting blood samples for checking Scvo2, the blood is collected from the superior vena cava by placing a thin, fibreoptic central venous catheter in the jugular vein. Arterial blood is then deoxygenated in tissues. Tissue oxygen extraction depends on their demand but also on their ability for oxygen extraction.

Therefore, after peripheral oxygen extraction, venous oxygen content depends on arterial content and tissue oxygen extraction. Pathophysiology of Circulatory Failure Shock is one of the leading causes of admission in the intensive care unit.

Difference between Scvo2 and Svo2 | Difference Between | Difference between Scvo2 vs Svo2

Though the magnitude of macrocirculatory disorders is well known to be related to prognosis [ 2 ], its optimization seems mandatory [ 3 ] but insufficient [ 4 ].

Indeed, in septic shock patients, Sakr et al. Schematically, as represented in Figure 1any fall in DO2 is initially compensated by an increase in tissue oxygen extraction EO2explaining that tissue VO2 is initially maintained. However, when tissue oxygen extraction capacity is overtaken, oxygen consumption begins to fall and lactate concentration increases, indicating a switch of the cellular metabolism from aerobic glycolysis to cytoplasmic anaerobic glycolysis.

This threshold immediately precedes the onset of clinical organ failures.

Difference between Scvo2 and Svo2

By the time the blood reaches the pulmonary artery, all venous blood has "mixed" to reflect the average amount of oxygen remaining after all tissues in the body have removed oxygen from the hemoglobin. The mixed venous sample also captures the blood before it is re-oxygenated in the pulmonary capillary. Because pulmonary artery catheter use has declined dramatically, ScvO2 measurements obtained from internal jugular or subclavian catheters are often used and interpreted in the same manner.

An ScvO2 refers to a central venous sample.

relationship between svo2 and scvo2 in shock

An ScvO2 measurement is a surrogate for the SvO2. It may be used to identify changes in a patient's tissue oxygen extraction. We usually assume possibly incorrectly at times that a blood gas sample obtained from the internal jugular or subclavian which reflects only head and upper extremities will have the same meaning as an SvO2.

What does it tell us? Mixed venous oxygen saturation SvO2 can help to determine whether the cardiac output and oxygen delivery is high enough to meet a patient's needs.

relationship between svo2 and scvo2 in shock

It can be very useful if measured before and after changes are made to cardiac medications or mechanical ventilation, particularly in unstable patients. What are the normal values? How do I use this information clinically? ATP energy is needed for all cell function and survival.

Tissues require oxygen in order to make ATP energy.

  • SvO2 vs ScvO2

If the amount of oxygen being received by the tissues falls below the amount of oxygen required because of an increased need, or decreased supplythe body attempts to compensate as follows: